The Significance of the “KGS Practice” in Pathology and Oncology Part 12
PART 12: KGS CLINICAL MANAGEMENT (Article PART 3)
Part 3: KGS CLINICAL MANAGEMENT
KGS Prognostic Profile
Made up by periodic KGS Index values and displayed by the KGS Prognostic Chart(KGS Chart), KGS Prognostic Profile provides the periodic sets of prognostic details of clinical cases functioning as a basic part of KGS pathology reports and patient files (Tables 5-8).
KGS Prognostic Ranges
While the parametric KGS scores make up the KGS Index through the rational numbers directly generated from the cell counting and metastatic scale, the variable levels of the scores of the index generate the KGS Prognostic Ranges (Table 4) which provide a highly important straight referential guide in the KGS with a great deal of diagnostic importance and value.
KGS Prognostic Ranges
KGS Index KGS Prognostic Range
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<1 Normal Range (N)
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1-7.99 Low Range (L)
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8-18.99 Medium Range (M)
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19-29.99 High Range (H)
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30-40 Extreme Range (E)
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>40 Ultimate Range (U)
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Table 4: The KGS Prognostic Ranges. The prognostic KGS ranges, highly important and crucial to use in the prognostic follow-up in clinical oncology, are used for both malignant and benign tumors. Range levels are determined by the ranges of the “KGS Index” whose variable limits of numerical values directly make up the levels. The “Normal”(N) range level with the KGS Index of “<1” covers normal tissues and regressive tumors that have fully regressed to normality.
KGS Prognostic Chart (KGS Chart)
The “KGS Prognostic Chart” (KGS Chart) is the statistical distribution display of the clinical prognosis. It presents the KGS Prognostic Profile with the changing KGSPrognostic Ranges and KGS Grades within the progression of the KGS Index through the prognostic period. It is a very important guiding tool in clinical case management and in prospective and retrospective research studies (Figures 4-6).
IIIB….IVB….VA…..VIB…VIIA..VIIB….VIIR5…VIIR4..VIIR2..VIIR1..VIIR0…..I…
U…………………………………………………………………………………………………………………
……………………………………………….41.10………………………………………………………….
E…………………………………….37.54………….35.20……………………………………………….
……………………………………………………………………………………………………………………
H…………………………..26.85………………………………27.60…………………………………….
……………………14.65…………………………………………………16.20……………………………
M………………………………………………………………………………………………………………..
……………8.40…………………………………………………………………….11.10…………………
L…………………………………………………………………………………………………………………
…..5.25………………………………………………………………………………………..4.90………..
N…………………………………………………………………………………………………………..0.70
25.06.11….ı……..ı………ı……….ı………ı…………ı………..ı……….ı………..ı………ı..18.06.12
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Figure 4: KGS Prognostic Chart (KGS Chart).This example of the standard KGS Prognostic Chart (KGS Chart) shows the chronological profile of a benign (Grade III) tumor and its progressive transformation into a Grade VIIB malignant tumor as well as its dramatic full regression to normalty (Grade I) through a one-year successful oncotherapy period. This striking pattern of display of the KGS’s paradigmalprognostic chronological tumor profile is one of the unique and unprecedented guiding features of the KGS Prognostic Chart (KGS Chart). Prognostic KGS Ranges: N=Normal, L=Low, M=Medium, H=High, E=Extreme, U=Ultimate. KGS Grades: I: Normal grade; IIIB: Hyperplastic (Non-neoplastic) grade; IVB: Metaplastic (Pre-neoplastic) grade; VA: Dysplastic (Pre-neoplastic) grade; VIB: Neoplastic grade; VIIA, VIIB: Anaplastic grades; VIR5, VIR4, VIR, VIR2, VIR1 and VIR0: Regressive neoplastic grades. The dates of the KGS pathology reports are shown below the base line.
Copyright © 2010-2015 M. M. Karindas, MD
